A young someone doesn't recall (or forgets his reading of) the three decades of terrorism in Europe from the 1960's to the 1980's, or the impact of anarchists (the Islamic fundamentalists of the 1900's +/-) on American politics. Instead, this friend of MountainRunner who has my respect, has clearly drunk too much of the 4GW Kool-Aid that all things are new and unique to our time.
Another MountainRunner friend casts the destabilizing event as it should be: a political attack. Last I checked, Israel and Mexico were outside the gap, as is Russia, as well as others that have suffered politically motivated and destabilizing attacks.
By viewing this event as SOP, we might be inclined to write something like "blah blah blah" instead of a real analysis of the consequences. In our modern global environment, economic and physical insecurity provide a breeding ground for hate and isolationism that can easily travel outside the region on instant communication and transportation networks. We care what happened and must not dismiss the act as something it is not.
What will be the impact from her death? Nothing good, regardless how ruthless she was. Remember she had substantial public support and was one of two returning opposition leaders that were helping force change in Pakistan.
That said, I haven't had the cycles to follow Pakistan closely enough to prognosticate what comes next, so I'll punt this question to me over to Tom.
Update: another MR friend, Abu Muqawama has more immediate questions on his mind and a link to an interesting discussion.
Update II: Tom has his post up. There are other smart posts out there, see SWJ for a listing.

"A young someone doesn't recall (or forgets his reading of) the three decades of terrorism in Europe from the 1960's to the 1980's, or the impact of anarchists (the Islamic fundamentalists of the 1900's +/-) on American politics.
MR,
How so?
I'm unaware of a period during the Marxist inusrgency in western Europe where it was expected that the leading opposition candidate would be murdered, nor where it was widely suspected the incumbent government LIHOP. Ditto the Anarchists who, whateve their charms, where not tolerated as useful idiots by either Republican or Democratic administrations.
" Instead, this friend of MountainRunner who has my respect, has clearly drunk too much of the 4GW Kool-Aid that all things are new and unique to our time."
I don't mention 4GW in the post, nor do I even use the words "new" or "unique." Heck, I've argued that 4GW is at least two thousand years old [1]!
"By viewing this event as SOP, we might be inclined to write something like "blah blah blah" instead of a real analysis of the consequences."
Hehe. Can't plead innocent to that one!
My rhetorical point was mostly in contrast to Robert Patterson [2], who seems to view this as the end of contemporary civilization -- an event of the magnitude of Sarejevo 1914. My point is that, like so much evil in the Gap, it's not out of the range of normal variation.
[1] http://www.tdaxp.com/archive/2006/03/30/jesusism-paulism-introduction-the-revolution-of-early-christ.html
[2] http://smartpei.typepad.com/robert_patersons_weblog/2007/12/bhutto-murdered.html